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Cancer treatment: Can stem cell transplants fight cancer? | Health


For more than 30 years, stem cells have been used to repair the blood and immune system destroyed by cancer cells, as well as during cancer treatment with chemotherapy or radiation. Besides their utility in immune reconstitution, stem cells have been shown to help with tissue regeneration and as a vehicle in cancer therapies.

The current concept of “cancer stem cells” has pushed the scientific community into a vast new area of ​​research and potential future cancer treatments, but cancer stem cells are the main What is corpse? In an interview with HT Lifestyle, Dr Pradeep Mahajan, Regenerative Medicine Researcher and Founder of StemRx Bioscience Solutions in India, explains: “They are like cancer-fighting stem cells. . They do not. They are cancer-causing cells. Previously, experts believed that all cancer cells were the same. There is now evidence that specific, fast-growing cancer stem cells keep your disease alive by multiplying. Treatments that target cancer stem cells have recently become important when combined with standard drugs to treat cancer and avoid recurrence.”

Proposing immunotherapy to target cancer cells, he said: “Immunotherapy is a treatment for cancer. It strengthens the immune system and helps the body detect and destroy cancer cells using compounds made by the body or in a laboratory. Immunotherapy can be used to treat many types of cancer. It can be used alone or along with chemotherapy and/or other cancer therapies.”

He added: “Different forms of cancer are fought off by different cells. For example, one way the immune system attacks cancer is to release T cells, a type of white blood cell. T cells. treat cancer as “foreign” cells that don’t belong in the body T cells fight and try to get rid of the malignant cells This can help control side effects when treatment is targeted and if there are any additional new modalities. Targeting breast tumors or solid tumors of the brain, chemotherapy molecules can reach the targeted cancer cells.”

Talking about whether stem cell transplants can fight cancer, he revealed: “Stem cell transplants usually don’t fight cancer directly. Instead, they aid in restoring your body’s ability to make stem cells after treatment with extremely high doses of radiation, chemotherapy, or both. However, in multiple myeloma and some types of leukemia, a stem cell transplant can directly combat the malignancy. This is due to a phenomenon known as graft versus tumor, which can develop after an allogeneic transplant. Graft-versus-tumor occurs when white blood cells from a donor (graft) attack any cancer cells left in your body after high-dose treatment (tumor). This effect increases the effectiveness of the therapies.”

He assures: “Stem cell transplantation is a treatment that restores hematopoietic stem cells for people whose stem cells have been damaged by intense chemotherapy or radiation therapy used to treat certain diseases. malignant disease. Stem cell/bone marrow transplantation is commonly used to control cancer. Some malignancies, such as certain types of leukemia and lymphoma, are treatable. For other diseases, cancer remission is the greatest potential outcome. When in remission, there are no signs or symptoms of cancer.”

He advises that you see your doctor and undergo regular testing after a transplant, “This is to monitor for any symptoms of cancer or problems with the transplant, as well as to prevent any complications. any side effects you may experience. This follow-up treatment is crucial to your rehabilitation.

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