The 15 Best Anti-Aging Moisturizers for Your 30s, 40s, and 50s

Known simply as “The Cream” for a reason, this beloved moisturizer was developed by scientist Augustinus Bader after he worked with teenage burn victims. . This moisturizer (also in a Rich version) is infused with the same TFC8 molecule that Bader uses to help heal burn victims’ skin.

Board-certified dermatologist Rosemarie Ingleton drew inspiration from the natural wonders of her hometown of Jamaica while creating this silky-smooth face cream. It’s made with a Jamaican Superfruit blend (blueberry, orange, cane, lemon, sugar maple, plus hyaluronic acid) to brighten, hydrate, and smooth skin all at once.

This refillable moisturizer smells and feels great. Chanel researched red camellias for a decade, discovering that the oil and extract combined smooth, plump, and brighten skin.

This super-thick cream has a 30% concentration of proxylane, a sugar molecule that keeps skin plump and hydrated. There are also barrier repair ingredients and antioxidants to fight existing signs of aging and prevent future wrinkles.

The air pump keeps this thick cream – filled with gold-starved anti-aging ingredients like growth factors, amino acids and peptides – strong until you’re smooth on the skin.

Two favorite anti-aging ingredients – retinol and hyaluronic acid – and fragrance-free come together in this nighttime treatment. Moisturizing lasts for 48 hours and it’s gentle enough for sensitive skin.

Hyaluronic acid, vitamin C and pro-retinol (a very stable form of retinol that won’t irritate your skin) combine into a thick cream that works overnight to fight the signs of aging.

Known for their ultra-soothing products, CeraVe’s nighttime moisturizer uses hydration to leave skin plump and looking younger. Formulated with niacinamide, peptides and hyaluronic acid, this night cream uses patented technology to keep your skin hydrated all day.

If you want a lightweight yet powerful moisturizer, this is it. Ceramides, vitamin F (which strengthens the moisture barrier), coconut, red algae extract and pomegranate sterols combine into a cooling cream that feels great on skin (especially if you’re super dry or after laser treatment).

Lipids from acai berry and plant-derived squalane make this moisturizer super hydrating and nourishing.

This ultra-rich version of this iconic moisturizer is made with vitamin B3 and peptides and is free of parabens, phthalates, dyes and synthetic fragrances.

This twice-a-day treatment for your face features an anti-aging trio: vitamin A, chaga mushroom, and hyaluronic acid. These ingredients work in tandem to even out skin tone, smoothen, and reduce wrinkles. It even works on the neck and can also help against technology-induced neck.

There are 19 different anti-inflammatory botanicals in this oil-based moisturizer, which work synergistically with retinol and peptides to soothe and smooth skin.

Vitamin-rich water from the Swiss Alps fortifies the cream, which starts out thick but quickly melts into the skin. It also has vitamin C to brighten skin tone and peptides to help firm the skin.

There are two separate compartments inside this pot: The purple cream is super dense and uses hyaluronic acid, soybeans, and yeast to plump and hydrate; White gel cream instantly tightens with sweet almond and whey protein. Layer together for final processing.